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Continuum of Care in Hospitalized Patients With Opioid Use Disorder and Infectious Complications Fr1
Elana Rosenthal
Opioid Use Disorder
Injection Related Infections
This is a three-group randomized controlled trial conducted at five hospitals across the
U.S. designed to test the effectiveness of two interventions (1) Integrated infectious
diseases and Medication for Opioid Use Disorder outpatient clinic (IC) and (2) NavSTAR
Intervention (NS) compared to treatm1 expand
This is a three-group randomized controlled trial conducted at five hospitals across the U.S. designed to test the effectiveness of two interventions (1) Integrated infectious diseases and Medication for Opioid Use Disorder outpatient clinic (IC) and (2) NavSTAR Intervention (NS) compared to treatment as usual aimed at reducing infection related readmissions and improving health outcomes in people hospitalized with an infection related to injecting opioids. Type: Interventional Start Date: Oct 2024 |
Luteolin for the Treatment of People With Schizophrenia
University of Maryland, Baltimore
Schizophrenia
Schizoaffective Disorder
Luteolin is a natural product found in foods such as celery, green pepper, parsley, and
chamomile tea. It has been found to have anti-cancer, anti-oxidant, and anti-inflammatory
properties. The purpose of this study is to determine if luteolin helps improve symptoms
of schizophrenia. expand
Luteolin is a natural product found in foods such as celery, green pepper, parsley, and chamomile tea. It has been found to have anti-cancer, anti-oxidant, and anti-inflammatory properties. The purpose of this study is to determine if luteolin helps improve symptoms of schizophrenia. Type: Interventional Start Date: Jun 2022 |
Diaphragm Structure and Function in Children
University of Maryland, Baltimore
Respiratory Muscle Training
The purpose of this research is to study the feasibility of a specific training program
for the breathing muscles (inspiratory muscle training) and the effects on how breathing
is regulated during exercise in typically developing children. expand
The purpose of this research is to study the feasibility of a specific training program for the breathing muscles (inspiratory muscle training) and the effects on how breathing is regulated during exercise in typically developing children. Type: Interventional Start Date: Mar 2024 |
Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT
Major Extremity Trauma Research Consortium
Post Operative Surgical Site Infection
The proposed study is a multi-center, prospective randomized controlled trial comparing
current standard of care treatment to the SEXTANT treatment protocol in patients with
Type III open fractures of the tibia and IIIB fractures of the ankle and hindfoot. expand
The proposed study is a multi-center, prospective randomized controlled trial comparing current standard of care treatment to the SEXTANT treatment protocol in patients with Type III open fractures of the tibia and IIIB fractures of the ankle and hindfoot. Type: Interventional Start Date: May 2021 |
ROSE-Longitudinal Assessment With Neuroimaging
University of Cincinnati
Intracerebral Hemorrhage
The investigators will perform follow-up on 250 of 500 cases recruited into the ROSE
study of cases with deep and lobar intracerebral hemorrhage to perform advanced
neuroimaging at 12-24 months post stroke, and evaluations of motor and cognitive function
at baseline, 6 months after baseline, and 121 expand
The investigators will perform follow-up on 250 of 500 cases recruited into the ROSE study of cases with deep and lobar intracerebral hemorrhage to perform advanced neuroimaging at 12-24 months post stroke, and evaluations of motor and cognitive function at baseline, 6 months after baseline, and 12 months after baseline to determine predictors of recovery, progressive cognitive or functional impairment. The investigators propose to leverage the recruitment, DNA, RNA-seq and baseline advanced neuroimaging cohort of ROSE to obtain long-term neuroimaging and identical assessments longitudinally to address critical questions regarding the progressive decline of patients 12 to 24 months post intracerebral hemorrhage (ICH) with long term cognitive follow-up to 36 months on average. This proposal would represent the largest, and longest advanced neuroimaging and RNA-sequencing evaluation after ICH to date. Type: Observational Start Date: Sep 2020 |
2-level Cervical Disc Replacement Comparing Prodisc C SK & Vivo to Mobi-C
Centinel Spine
Symptomatic Cervical Disc Disease
A multi-center, prospective, randomized, controlled comparison of the prodisc C SK and
prodisc C Vivo to the control, a similar, legally marketed total disc replacement device
in subjects with symptomatic cervical disc disease (SCDD). expand
A multi-center, prospective, randomized, controlled comparison of the prodisc C SK and prodisc C Vivo to the control, a similar, legally marketed total disc replacement device in subjects with symptomatic cervical disc disease (SCDD). Type: Interventional Start Date: Aug 2019 |
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