Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
Purpose
This study is a pre-screening process used to assess participants' potential eligibility for Roche interventional Alzheimer's disease studies.
Condition
- Alzheimers Disease
Eligibility
- Eligible Ages
- Between 50 Years and 90 Years
- Eligible Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- Ability and willingness to participate in an interventional clinical study, including meeting key eligibility criteria of linked interventional Roche AD studies (e.g., specific age ranges) - Ability and willingness to receive information about potential eligibility in an associated interventional Roche AD study
Exclusion Criteria
- Dependency in basic activities of daily living (bADLs) due to cognitive impairment - Visual or auditory impairment that would prevent them from performing the cognitive assessments (eyeglasses and hearing aids are permitted) - Any self-reported evidence or known diagnosis of a neurological or neurodegenerative condition that may lead to cognitive impairment other than AD - History of severe, clinically significant central nervous system trauma - Any serious medical condition that precludes a participant's safe participation and completion of a clinical study - For participants with a clinical diagnosis of MCI or mild AD: Previous AD diagnosis based on biomarker confirmation with an approved or validated rule in method (e.g., amyloid PET or cerebrospinal fluid, blood biomarker) is exclusionary
Study Design
- Phase
- Phase 3
- Study Type
- Interventional
- Allocation
- N/A
- Intervention Model
- Single Group Assignment
- Primary Purpose
- Screening
- Masking
- None (Open Label)
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
|
Other Screening Arm |
Participants will be assessed for their concentration of pTau217 in blood and cognitive score in the International Shopping List Test (ISLT). |
|
Recruiting Locations
More Details
- Status
- Recruiting
- Sponsor
- Hoffmann-La Roche
Study Contact
Reference Study ID Number: WP45722 https://forpatients.roche.com/ No attachments to email below.888-662-6728 (U.S. and Canada)
global-roche-genentech-trials@gene.com