Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy, with the peak incidences occurring in children two to five years of age. Children with ALL received neurotoxic chemotherapy agents for two to three years that causes decreased distal muscle strength and poor timing of muscle activation. After completion of medical treatment, ALL childhood cancer survivors (ALL CCS) are more likely to have an inactive lifestyle, resulting in life-long gross motor proficiency differences compared to their peers. ALL CCS typically do not utilize physical therapists' expertise after medical treatment has been completed. There are limited physical therapy (PT) intervention studies for ALL CCS.



Eligible Ages
Between 6 Years and 17 Years
Eligible Genders
Accepts Healthy Volunteers

Inclusion Criteria

  • Children 6-17 years old - Completed medical treatment for ALL within the past five years (1 to 60 months) - Speak English.

Exclusion Criteria

  • Diagnosis of a neurological disorder such as cerebral palsy, Down syndrome - Currently receiving PT services.

Study Design

Study Type
Intervention Model
Single Group Assignment
Intervention Model Description
Feasibility study
Primary Purpose
None (Open Label)
Masking Description
the physical therapist performing the baseline and post-training does not have involvement with the intervention

Arm Groups

ArmDescriptionAssigned Intervention
One group that all receive the intervention of jumping rope.
All participants will be in one group. Every participant receives the same intervention.
  • Behavioral: JUMP
    Warm-up, stretching, jumping rope, cool-down

More Details

University of Maryland, Baltimore

Study Contact

Detailed Description

We are performing a feasibility study to examine a movement based intervention that utilizes fast movements through jumping rope to improve balance, coordination, movement speed, and movement agility. The abilities to generate fast movements are required to perform functional activities and for playing sports. Participants will receive five in-person PT sessions and a home program for six weeks. The goal of this research is to determine the feasibility, acceptability, and promise of a PT program that emphasizes fast movements in ALL CCS.


Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.